Supplemental Data Formation of the BMP Activity Gradient in the Drosophila Embryo

Supplemental Figures S2-S6 show how three characteristics of the dorsal midline peak of [LR] vary when several of the critical parameters are altered, pairwise, over a substantial range from the “base” parameter set of Figure 5. In each figure, the top left image depicts the peak height at 38 min, the time given in Figure 6. The top right image depicts peak height at 90 min. This was used, rather than steady-state peak height, because for some parameter sets, steady state occurs later than 90 min, a time too long to be biologically significant. The lower left image depicts the time required for the height of the [LR] peak to achieve 63.2% (1-e) of its 90 min value; this gives a sense of the overall rate of formation of the BMP activity gradient. The point at the very center of each square represents the parameter set used is Figure 5.